Table 2.
Characteristics of Studies Included in the meta-analysis of TyG index in NAFLD/MALFD participants.
| Author | Year | Country | Age | Disease | AUC (95% CI) | Design | Reference Standard | Samples | Cut-Off | tp | fp | fn | tn |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mengte Shi et al [21]. (1) | 2021 | China | ≤18 | no | 0.733 (0.698, 0.768) | RP | ultrasonography | 1291 | 8.42 | 165 | 300 | 96 | 730 |
| Mengte Shi et al [21]. (2) | 2021 | China | ≤18 | no | 0.769 (0.719, 0.818) | RP | ultrasonography | 554 | 8.42 | 75 | 113 | 37 | 329 |
| Mohammad E. Khamseh et al [35]. |
2021 | Iran | 30–65 | obesity | 0.676 (0.598, 0.754) | RP | Transient elastography | 184 | - | 76 | 41 | 20 | 47 |
| Shujun Zhang et al [10]. | 2017 | China | ≥20 | no | 0.782 (0.773, 0.790) | RP | ultrasonography | 10,761 | 8.5 | 3140 | 1892 | 1209 | 4520 |
| Wen Guo et al [22]. | 2020 | China | ≥18 | no | 0.761 (0.747, 0.774) | RP | ultrasonography | 4784 | 8.7 | 2049 | 582 | 853 | 1300 |
| Fangfei Xie et al [23]. | 2021 | China | ≥18 | no | 0.807 (0.785, 0.828) | RP | ultrasonography | 1748 | 4.75 | 379 | 312 | 147 | 910 |
| A Reum Choe et al [37]. (1) | 2020 | Korea | ≥18 | CKD | 0.85 (0.80, 0.90) | RP | ultrasonography | 567 | 0.146 | 72 | 109 | 17 | 369 |
| A Reum Choe et al [37]. (2) | 2020 | Korea | ≥18 | CKD | 0.84 (0.78, 0.90) | RP | ultrasonography | 252 | 0.146 | 46 | 65 | 5 | 136 |
| Guotai Sheng et al [24]. | 2021 | Japan | - | no | 0.8084 (0.7996, 0.8173) | RP | ultrasonography | 14,251 | 8.2059 | 1899 | 3348 | 608 | 8396 |
| Liu Yiting et al [25]. | 2021 | China | 18–80 | no | 0.816 (0.811, 0.820) | RP | ultrasonography | 25,535 | 6.9 | 9022 | 4104 | 2595 | 9814 |
| Jingrui Wang et al [26]. | 2021 | China | 19–93 | no | 0.725 (0.705, 0.746) | RP | ultrasonography | 3239 | 8.55 | 534 | 1061 | 178 | 1466 |
| Nong Li et al [27]. | 2021 | China | - | T2D | 0.651 (0.611, 0.691) | RP | ultrasonography | 826 | 6.5 | 291 | 73 | 261 | 201 |
| Chen Huanan et al [28]. | 2020 | China | >60 | no | 0.60 (0.58, 0.61) | RP | ultrasonography | 46,693 | 8.63 | 2851 | 13,951 | 2809 | 27,082 |
| Rongjiong Zheng et al [29]. | 2018 | China | ≥18 | no | 0.76 (0.74, 0.77) | P | ultrasonography | 4539 | 8.52 | 935 | 885 | 455 | 2264 |
| Xiaolin Ye et al [30]. | 2021 | China | 3–14 | no | 0.765 (0.682, 0.835) | RP | ultrasonography | 134 | 8.16 | 52 | 25 | 12 | 39 |
| Yaling Li et al [31]. | 2020 | China | 14–90 | no | 0.7264 (0.7096, 0.7433) | P | ultrasonography | 9767 | 8.3219 | 590 | 3280 | 251 | 5646 |
| Huanhuan Yang et al [32]. | 2018 | China | >60 | no | 0.793 | RP | ultrasonography | 918 | - | 80 | 123 | 17 | 239 |
| Chao Cen et al [33]. (1) | 2020 | China | 18–75 | no | 0.774 (0.767, 0.781) | RP | ultrasonography | 16,468 | 6.95 | 4470 | 2960 | 1791 | 7247 |
| Chao Cen et al [33]. (2) | 2020 | China | 18–75 | no | 0.783 (0.769, 0.796) | RP | ultrasonography | 5000 | 6.87 | 1320 | 1002 | 439 | 2239 |
| I-Ting Lin et al [34]. (1) | 2021 | China | - | MetS | 0.697 | RP | ultrasonography | 764 | - | 262 | 155 | 92 | 255 |
| I-Ting Lin et al [34]. (2) | 2021 | China | - | MetS | 0.747 | RP | ultrasonography | 1205 | - | 373 | 284 | 99 | 449 |
| Kyungchul Song, et.al [38]. | 2021 | Korea | 10–19 | no | 0.667 (0.636, 0.697) | RP | ALT (>26 U/L for boys and >22 U/L for girls) | 3728 | 8.391 | 215 | 895 | 190 | 2428 |
| Ehsaneh Taheri et.al [36]. | 2022 | Iran | 35–70 | obesity/T2D | 0.862 (0.856, 0.877) | RP | Fatty liver index ≥ 60 Overweight or obese/T2DM |
1932 | 8.62 | 790 | 447 | 178 | 517 |
| Hwi Seung Kim et al [39]. | 2022 | Korea | - | obesity | 0.770 (0.762, 0.778) | RP | ultrasonography | 10,585 | - | 2728 | 3331 | 556 | 3970 |
RP, retrospective; P, prospective; fn, False Negative; fp, False Positive; tn, True Negative; tp, True Positivity.