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. Author manuscript; available in PMC: 2023 Nov 8.
Published in final edited form as: Biomater Sci. 2022 Nov 8;10(22):6341–6353. doi: 10.1039/d2bm00844k

Figure 1. Correlation analysis to determine clinically relevant candidate proteins in patient serum samples.

Figure 1.

(A) Schematic describing our approach to identify clinically relevant candidate proteins that are significantly correlated with (1) quantified measurements of AVS severity in patients and (2) in vitro myofibroblast activation data. (B) Venn diagram showing the overlap between proteins significantly correlated (R>0.8) with at least one quantified measure of AVS severity and proteins significantly correlated (R>0.75) with myofibroblast activation in vitro. Full protein names for abbreviated proteins are shown in Supplemental Table 2. (C-D) Correlation plots comparing annexin A2 abundance and (C) patient STS score or (D) percent myofibroblast activation in vitro. (E-F) Correlation plot comparing cystatin C abundance and (E) patient STS score or (F) percent myofibroblast activation in vitro.