Table 5.

Association between egg intake and incidences of some major chronic diseases/mortality of major disease groups (RR, 95% C.I.). The dose-response meta-analysis always refers to an additional serving of a food per day relative to the average intake of that food observed in a cohort study (50 g for eggs).

Health Outcomes	Unit of Intake	RR (95% C.I.)	N° of Prospective Studies	References
Total Eggs
All-cause mortality	Highest vs. Lowest	1.06 (1.00–1.12)	8	[114]
	Dose-Response	1.15 (0.99–1.34)	5 /	[114] [115]
Total CVDs mortality	Highest vs. Lowest	No data
	Dose-Response	0.95 (0.88–1.03)	8	[164]
Total CVDs incidence	Highest vs. Lowest	No data
	Dose-Response	0.94 (0.89–0.99)	9	[164]
CHD	Highest vs. Lowest	/ /	6 11	[131] [118]
	Dose-Response	/ / / /	6 9 / 12	[165] [118] [115] [164]
Stroke	Highest vs. Lowest	/	10	[118]
	Dose-Response	/	10 /	[118] [115]
		0.97 (0.93–1.02)	6	[164]
		0.91 (0.81–1.02)	6	[165]
HBP	Highest vs. Lowest	0.54 (0.32–0.91)	1	[120]
	Dose-Response	0.25 (0.08–0.74)	1
CHF	Highest vs. Lowest	1.25 (1.12–1.39)	4	[118]
	Dose-Response	1.16 (1.03–1.31)	4
		1.11 (0.99–1.25)	4	[164]
T2D	Highest vs. Lowest	/	5	[121]
	Dose-Response	/ /	/ 13	[115] [122]
		1.16 (1.09–1.23)	13	[166]
Overweight/Obesity	Highest vs. Lowest	No data
	Dose-Response	No data
MetS	Highest vs. Lowest	No data
	Dose-Response	No data
Total cancer mortality	Highest vs. Lowest	No data
	Dose-Response	No data
Total cancer incidence	Highest vs. Lowest	No data
	Dose-Response	No data
CRC	Highest vs. Lowest	1.35 (1.11–1.36)	4	[124]
	Dose-Response	/ /	3 /	[124] [115]
Breast cancer	Highest vs. Lowest	/	9	[127]
	Dose-Response	/	8
Gastric cancer	Highest vs. Lowest	/	9	[128]
	Dose-Response	No data