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. 2022 Dec 1;14(23):5948. doi: 10.3390/cancers14235948

Figure 1.

Figure 1

p53 family members. (A) Representation of the different domains in p53 and TA and ΔN p63α and p73α isoforms: transactivation domain (TA, in light grey), DNA binding domain (DBD, in red), oligomerization domain (OD, in yellow), sterile alpha domain (SAM, in dark grey), and the transactivation inhibitory domain (TID, in orange), introns (black lines). (B) Represents p53, p63, and p73 multiple spliced variants. P stands for different promoters, numbered boxes indicate exons, black boxes are untranslated sequences, and black lines are introns.