Table 2.
Predicted pre-ADMET results of flavonoids acetamide derivatives from Ames test.
| Compounds | Toxicity Prediction | Name of Test | Result |
|---|---|---|---|
| 4 | Ames | Ames TA100 (+S9) | Negative |
| Ames TA100 (−S9) | Negative | ||
| Ames TA1535 (+S9) | Negative | ||
| Ames TA1535 (−S9) | Negative | ||
| Carcinogenicity | Carcinogenicity (Mouse) | Negative | |
| Carcinogenicity (Rat) | Negative | ||
| 11 | Ames | Ames TA100 (+S9) | Negative |
| Ames TA100 (−S9) | Negative | ||
| Ames TA1535 (+S9) | Negative | ||
| Ames TA1535 (−S9) | Negative | ||
| Carcinogenicity | Carcinogenicity (Mouse) | Positive | |
| Carcinogenicity (Rat) | Negative | ||
| 15 | Ames | Ames TA100 (+S9) | Negative |
| Ames TA100 (−S9) | Negative | ||
| Ames TA1535 (+S9) | Negative | ||
| Ames TA1535 (−S9) | Negative | ||
| Carcinogenicity | Carcinogenicity (Mouse) | Positive | |
| Carcinogenicity (Rat) | Negative | ||
| 5 | Ames | Ames TA100 (+S9) | Negative |
| Ames TA100 (−S9) | Negative | ||
| Ames TA1535 (+S9) | Negative | ||
| Ames TA1535 (−S9) | Negative | ||
| Carcinogenicity | Carcinogenicity (Mouse) | Negative | |
| Carcinogenicity (Rat) | Negative | ||
| 7 | Ames | Ames TA100 (+S9) | Negative |
| Ames TA100 (−S9) | Negative | ||
| Ames TA1535 (+S9) | Negative | ||
| Ames TA1535 (−S9) | Negative | ||
| Carcinogenicity | Carcinogenicity (Mouse) | Negative | |
| Carcinogenicity (Rat) | Negative |