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. 2022 Nov 22;27(23):8133. doi: 10.3390/molecules27238133

Table 3.

Drug relevant and toxicity prediction scores of flavonoid acetamide derivatives from Osiris property explorer.

Compound Toxicity Drug-Relevant Properties
Irritant Effect Reproductive Effect Tumorigenicity Mutagenic Effect cLogP Drug-Likeness Solubility Drug Score
4 Green Green Green Red −2.33 1.57 −2.96 0.36
11 Green Red Green Green 0.35 2.71 −3.19 0.48
15 Green Green Green Green −0.99 1.95 −3.06 0.71
5 Green Green Green Red −2.09 −2.36 −3.48 0.18
7 Green Green Green Red −0.66 −5.47 −3.57 0.20

Green color indicates no risk or low risk, red color indicates more toxicity risk.