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. 2022 Dec 10;22:399. doi: 10.1186/s12935-022-02804-7

Table 2.

List of UA derivates having anti-cancer activity

Derivatives Modification site Anticancer activity Cell line References
UA1-UA8 C-28 Antiproliferative activity MCF-7, Hela, and A549 [11]
UA11b, UA7b C-28 Cell cycle arrest, HIF1- α expression SMMC-7721 and HepG2 [12]
FZU3010 C-28 Proliferation inhibition, Induction of apoptosis SUM149PT, HCC1937 [14]
UA1a-2c C-3 Apoptosis, Cell cycle arrest VERO, HepG2 [16]
UA232 C-3, C-28 Induction of apoptosis A549, H460, MCF-7, HeLa [17, 18]