Table 2.
Overview of studies on clinical exercise testing and/or cardiac rehabilitation participation in patients recovering from spontaneous coronary artery dissection or aortic dissection
| Study | Participants No./%Female | Indication | Exercise test BP (mmHg) | CR exercise sessions | Aerobic training intensity | Exercise-related SAE |
|---|---|---|---|---|---|---|
| Corone et al., 200910 | 26/NR | De Bakey Type I | NR | 3–5 weekly | Avg. 11 RPE | None |
| Prospective (France) | Avg. total: 18 (range: 5–50) | Avg. SBP: 150 mmHg | ||||
| Delsart et al., 201632 | 105/30.5 | Stanford A and B | Cycle: Avg. BP at AT: 151/77 | NA | NA | None |
| Prospective (France) | ||||||
| Fuglsang et al., 201711 | 10/40 | Stanford A | Cycle: Pre-CR | 3 weekly over 12 weeks (36 sessions) | Referenced AHA/EAPC guidelines | None |
| Retrospective (Denmark) | Max Avg.: 200/95 | |||||
| Post CR | ||||||
| Max Avg.: 207/99 | Avg. total NR | |||||
| Hornsby et al., 202033 | 28/14 | Stanford A | 3.6 mo post-surgery | NA | NA | None |
| Retrospective (USA) | ||||||
| Treadmill: Max Avg.: 156/70 | ||||||
| Norton et al., 202134 | 21/14 | Stanford A | Treadmill: 3 mo post-surgery | NA | NA | None |
| Prospective (USA) | ||||||
| Max Avg.: 170/68 | ||||||
| 15 mo post-surgery | ||||||
| Max Avg.: 167/75 | ||||||
| Delsart et al., 202131 | 165/29.7 | Stanford A and B | Cycle: Max Avg.: 183/85 | NA | NA | None |
| Prospective (France) | ||||||
| Silber et al., 20159 | 9/100 | SCAD | NR | 1–3 weekly | 60%–70% HRR | None |
| Prospective (USA) | Avg. total: 28 (range: 5–39) | 12–14 RPE | ||||
| Chou et al., 20168 | 48/100 | SCAD | NR | 1 weekly | 50%–70% HRR | None |
| Prospective (Canada) | Avg. total: 12.4 | 12–14 RPE | ||||
| Krittanawong et al., 201612 | 269/97 | SCAD | NR | 1–3 weekly | NR | None |
| Retrospective (USA) | Avg. total: 18 | |||||
| Imran et al., 201817 | 10/80 | SCAD | Modality NR | 3 weekly over 12 weeks (36 sessions) | 70%–85% HRmax | None |
| Retrospective (USA) | Symptom limited up to SBP/DBP 140 and/or 90 | Exercise BP <140/90 mmHg | ||||
| 2 of 10 patients pre-planned to complete only 20 sessions | Rest to exercise rise in SBP ≤20 mmHg | |||||
| Avg. end-exercise BP NR | 4–6/10 RPE scale |
AT, anaerobic threshold; BP, blood pressure; CR, cardiac rehabilitation; HRmax, maximal heart rate achieved on pre-CR stress test; HRR, heart rate reserve; NA, not applicable/studied; NR, not reported; RPE, rating of perceived exertion (Borg, 6–20 scale); SAE, serious adverse events; SCAD, spontaneous coronary artery dissection.