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. 2022 Dec 10;20:521. doi: 10.1186/s12951-022-01736-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Characterization of the nano-nuclear-reactors. SEM (A) and TEM (B) image of Fe-PHCN. The scale bar represents 100 nm. C HRTEM images of Fe-PHCN. The scale bar represents 5 nm. D EDS elemental mapping of Fe-PHCN. E XPS characterization of Fe-PHCN. XPS high-resolution scans of Cu (F) and Fe (G) in Fe-PHCN. H Size of Fe-PHCN and Fe-PHCN@DOX by DLS measurement. I TEM image of Fe-PHCN@DOX. The scale bar represents 100 nm. J UV–vis spectrum of Fe-PHCN, DOX, and Fe-PHCN@DOX