Thomas et al.
Criteria	Yes	No	Other (CD, NR, NA)*
1. Was the study question or objective clearly stated?	☑
2. Were eligibility/selection criteria for the study population pre-specified and clearly described?	☑
3. Were the participants in the study representative of those who would be eligible for the test/service/intervention in the general or clinical population of interest?	☑
4. Were all eligible participants that met the pre-specified entry criteria enrolled?	☑
5. Was the sample size sufficiently large to provide confidence in the findings?	☑
6. Was the test/service/intervention clearly described and delivered consistently across the study population?	☑
7. Were the outcome measures pre-specified, clearly defined, valid, reliable, and assessed consistently across all study participants?	☑
8. Were the people assessing the outcomes blinded to the participants’ exposures/interventions?		☑
9. Was the loss to follow-up after baseline 20% or less? Were those lost to follow-up accounted for in the analysis?	☑
10. Did the statistical methods examine changes in outcome measures from before to after the intervention? Were statistical tests done that provided P values for the pre-to-post changes?		☑
11. Were outcome measures of interest taken multiple times before the intervention and multiple times after the intervention (i.e., did they use an interrupted time series design)?		☑
12. If the intervention was conducted at a group level (e.g., a whole hospital, a community, etc.) did the statistical analysis take into account the use of individual level data to determine effects at the group level?	☑

^*CD, Cannot determine; NA, Not applicable; NR, Not reported