Table 5. Predicted clearance of drugs as a function of prediction error ratio.
Error (ratio) | ADE | ||
---|---|---|---|
| |||
Preterm and term neonates (n=27), n (%) | >Neonates (n=60), n (%) | Total (n=87), n (%) | |
0.5–2 | 23 (85.2) | 57 (95.0) | 80 (92.0) |
0.5–1.5 | 20 (74.1) | 55 (91.7) | 75 (86.2) |
0.7–1.3 | 14 (51.9) | 40 (66.7) | 54 (62.1) |
>2 | 0 | 0 | 0 |
<0.5 | 5 (18.5) | 3 (5.0) | 8 (9.2) |
ADE: Age-dependent exponent