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. 2022 Dec 11;415(5):775–785. doi: 10.1007/s00216-022-04469-7

Table 3.

Storage stability of nicotinamide adenine dinucleotide (NAD+) and nicotinamide mononucleotide (NMN) in human whole blood at 4 °C

Storage period Storage stability (%)
NAD+ NMN
Mean SD %CV n Mean SD %CV n2)
2 days 123.7 23.8 19.3 9 52.1 20.4 39.1 9
1 week 134.9 19.8 14.7 4 27.81) NC NC 4 (2)
2 weeks 101.5 17.8 17.5 9 NC NC NC 9 (6)
1 month 64.4 5.9 9.1 9 65.7 34.1 51.8 9 (3)

Lower limit of quantification: 0.5 to 2 μM (NAD+), 0.25 to 1 μM (NMN)

Storage stability (%) = concentration after storage / concentration before storage (day 0) × 100

NC not calculated, as the concentrations in most samples were BLQ

1)The average value of two samples was calculated because the concentrations in two of the four samples were below the limit of quantification (BLQ)

2)Numbers in parentheses represent the number of exclusions based on BLQ