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Structure of VEGF-A/VEGFR-2 complex, PDB: 3V2A. Homodimeric VEGF-A (Green) binding to, and dimerization of, VEGFR-2 (Yellow). Key binding residues on VEGF-A helix-α1 (Phe17, Met18, Tyr21 and Tyr25) are highlighted in red. Reproduced with the permission of American Chemical Society.[12]
