TABLE 3.
Statistical descriptions of RISH, p16INK4a, and Ki-67
| Group | |||||
|---|---|---|---|---|---|
| HPV typing-negative | HPV typing-positive | Research (%) | Control (%) | P * | |
| RISH | |||||
| + | 28 | 278 | 93.3 | 100.0 | 1.0 |
| − | 2 | 0 | |||
| p16INK4a | |||||
| + | 28 | 273 | 93.3 | 98.2 | 1.0 |
| − | 2 | 5 | |||
| p16INK4a/Ki-67 | |||||
| + | 27 | 273 | 90 | 98.2 | 1.0 |
| − | 3 | 5 | |||
| RISH/p16INK4a | |||||
| + | 27 | 273 | 90 | 98.2 | 1.0 |
| − | 3 | 5 | |||
| RISH/p16INK4a/Ki-67 | |||||
| + | 27 | 273 | 90 | 98.2 | 1.0 |
| − | 3 | 5 | |||
*
P-value compared with different detection methods in the research group.
− indicates negative; +, positive; HPV, human papillomavirus; RISH, mRNA in situ hybridization.