Table 5.
The association of TCZ and SAR with DILI
Drugs | N | ROR | PRR | IC | EBGM |
---|---|---|---|---|---|
(95% two-sided CI) | (χ2) | IC025 | EBGM05 | ||
TCZ | 191 | 1.33 (1.14, 1.55) | 1.3 (13.27) | 0.36 (0.31) | 1.28 (1.13) |
SAR | 83 | 12.94 (9.6, 17.44)* | 7.31 (468.91)* | 2.83 (2.1)* | 7.11 (5.54)* |
TCZ-associated DILI ROR=1.33, 95% two-sided CI(1.14,1.55), PRR=1.3, χ2=13.27, EBGM=1.28, 95% one-sided CI=1.2; SAR-associated DILI ROR=12.94, 95% two-sided CI(9.6,17.44), PRR=7.31, χ2=468.91, EBGM=7.11, 95% one-sided CI=5.54; * means a strong signal that represents a strong statistical association between the drug and the adverse reaction