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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Allergy Clin Immunol. 2022 Jun 24;150(6):1525–1533. doi: 10.1016/j.jaci.2022.05.022

Figure 3. TTR family proteins are the prominent filarial antigens targeted by IgE antibodies and have diagnostic potential.

Figure 3.

a, ELISA analysis depicting TTR-specific antibody cross-reactivity profile to multiple TTR proteins. MAb 12D4, a human IgE mAb specific for WbSXP-1, served as negative control. OD, optical density. b, Proportion of filaria-specific antibodies binding different antigens. c, Binary heatmap showing presence (red) or absence (black) of antibody in indicated patient sera against filarial antigens tested in immunoblot analysis. Two serum samples (284 and 245) from respective mold- and shellfish-allergic patients served as negative controls.