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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Allergy Clin Immunol. 2022 Jun 24;150(6):1525–1533. doi: 10.1016/j.jaci.2022.05.022

Figure 4. IgH and IgL gene sequence analysis of filaria-specific IgE antibodies.

Figure 4.

Sixteen filaria-specific IgE antibodies were found to have unique sequences and were analyzed for genetic features. a, Heatmap showing the total number of unique sequences with corresponding V and J genes. b, CDR3 amino acid length distribution for heavy and light chains with indicated mean. c, IgH and IgL CDR3 amino acid number was determined using the ImMunoGeneTics (IMGT) database. d, Number of SHMs in the VH and VL chain of filaria-specific mAb genes.