Table 1.
Subject demographics and IgE encoding B cell frequencies
| Subject code |
Age | Sex | Diagnosis | Geographic location of infection |
Serum IgE IU/ml |
IgE B-cell frequency (per 107 PBMCs) |
IgE hybridomas generated |
|---|---|---|---|---|---|---|---|
| P1 | 61 | M | TPE | India | 4260 | 13.5 | 22 |
| P2 | 29 | M | TPE | India | 9810 | 8.1 | 1 |
| P3 | 21 | F | Loiasis | Cameroon | 20290 | 9.2 | 9 |
| P4 | 40 | M | Loiasis | Cameroon | 8520 | 10.9 | 12 |
| P5 | 61 | F | Loiasis | Cameroon | 11362 | 6.2 | 5 |
| P6 | 29 | M | Loiasis | Gabon | 7628 | 6.0 | 1 |
| P7 | 42 | M | Onchocerciasis | Sierra Leone | 8680 | 13.7 | 6 |
| P8 | 49 | F | TPE | India | 6140 | Serum only | Serum only |
| P9 | 27 | M | TPE | India | 7440 | Serum only | Serum only |
Subject helminth disease, geographic location of their infection, serum IgE titer, IgE B-cell frequency and IgE hybridomas yield are shown. IgE B cell frequencies are expressed as the number of IgE-positive cells per 10 million PBMCs. The total number of IgE-expressing human hybridomas generated for each subject is listed. No PBMCs, only sera, were used from subjects P8 & P9. TPE, tropical pulmonary eosinophilia.