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. 2022 Dec 12;25(3):330–340. doi: 10.1016/j.jcyt.2022.12.001

Figure 6.

Figure 6

Effect of IL-15 and dexamethasone on the IFN-γ production after co-culture with the combination of the SARS-CoV-2 peptide pools. IFN-γ production of SARS-CoV-2 specific CD45RA− memory T cells after co-culture with the combination of peptide pools in the presence or absence of IL-15 O/N and (A) dexamethasone O/N or (B) for 72 h. Several subsets are represented: CD45RA−CD3+, CD45RA−CD3+CD8+, CD45RA−CD3+CD4+. Black bars represent cells cultured in the absence of dexamethasone, dark color bars represent cells incubated with the different concentrations of dexamethasone and no IL-15 previous incubation, light color bars represent cells cultures with the different concentrations of dexamethasone previously exposed to IL-15. A Two-way ANOVA test was performed *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 N = 4. All donors had a previous COVID-19 infection. Mean and ± standard error of the mean.