Table 6.

Sensitivity, specificity, PPV, NPV and C-statistics of QRISK3 and FRS (patients with loss to follow-up were classified as the CVD group).

Tools	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	C-statistics (95% CI)
QRISK3†	59.4	93.6	96.7	42.6	0.665 (0.627, 0.704)
FRS†	50	77.6	73.5	55.5	0.638 (0.599, 0.677)
QRISK3††	93.5	75.0	92.1	78.8	0.661(0.621, 0.700)
FRS††	80.1	42.7	63.5	63.4	0.614 (0.574, 0.655)

†Dichotomised risk scores using a cut- off of 10% 10-year CVD. †† Dichotomised risk scores using a cut-off of 20% 10-year CVD. PPV, positive predictive value; NPV, negative predictive value; C-statistics, concordance statistics; QRISK3, QRESEARCH risk estimator version 3; FRS, framingham risk score.