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. 2022 Nov 28;12:888570. doi: 10.3389/fonc.2022.888570

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Copyright © 2022 Zhong, Yao, Liu, Zhang, Zhang, Zhang, Lin, Li, Li, Jiang, Cheng, Xu, Wen, Yang, Zhang, Cheng, Huang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of the metabolic characteristics of unsaturated fatty acids in ferroptosis-related molecular patterns and other factors affecting ferroptosis. (A–E) Differences in BUFAscore, AAMscore, LAMscore, ALAMscore, and hypoxia score in different ferroptosis-related molecular pattern groups in the GEO cohort, Kruskal–Wallis test. (F) Kaplan–Meier survival analysis of different cluster subtypes in the FScluster B of the GEO group, log rank test. (G) GSVA showed the activation levels of lipid metabolism pathways in different cluster subtypes. FScluster B of the GEO group. (H, I) Differences in genes and signaling pathways that affect ferroptosis among different ferroptosis-related molecular patterns, Kruskal–Wallis test, **P < 0.01; ***P < 0.001.