Table 4.
Indirect costs among women with breast cancer
| No. | First author | Reference year for costs | Region | Costing approach | Data gathering | Type of indirect cost | Cost (US dollars) |
|---|---|---|---|---|---|---|---|
| 1 | Mathias Lidgren [45] | 2005 | Sweden | HC | Not specified | Premature death | 165,695.42 |
| Missed days’ work | 20,167.36 to 48,407.67 | ||||||
| Total | 33,992.96 for women aged lower than 50 years | ||||||
| 24,724.97 for women aged 50–64 years | |||||||
| 2 | Rugile Ivanauskiene [40] | 2008 | lithuania | HC | Not specified | Premature death | 38,314,351.03 |
| Morbidity | 69,856,613.68 | ||||||
| Total | 150,204,061.57 | ||||||
| 3 | Steven Broekx [38] | 2006 | Belgium | HC | Not specified | Premature death | 33,930.20 per patient |
| Morbidity | 12,537.91 per patient | ||||||
| Total | 51,325.88 | ||||||
| 4 | Maneeta Jain [55] | India | HC | Not specified | Missed days’ work | 128,104.58 | |
| Unpaid | 297,548.46 | ||||||
| Total | 1,337,388.34 | ||||||
| Productivity loss | 14,014,584.40 | ||||||
| 5 | Błażej Łyszczarz [35] | 2010–2014 | Poland | HC | Not specified | Premature death | 103,782,672.49 |
| Morbidity | 126,857,360.69 | ||||||
| Missed days’ work | 79,153,502.28 | ||||||
| Unpaid help | 301,578.48 | ||||||
| Total | 434,722,812.46 | ||||||
| 6 | G. T. Vondeling [52] | 1990–2014 | Netherlands | HC | Not specified | Premature death | 331,729,844.30 |
| Morbidity | 354,937,281.96 | ||||||
| 7 | Eija Roine [58] | 2009–2010 | Finland | HC | Not specified | Mean loss productivity loss in primary treatment | 11,743.73 |
| Mean loss productivity loss in metatatic | 9794.59 | ||||||
| Sick leave | 11,219.12 | ||||||
| Informal care | Primary treatment = 2895.30 | ||||||
| Metas = 3944.53 | |||||||
| 8 | Justin G. Trogdon [51] | 2015 | United State | HC | Not specified | The value of lost work and home productivity days associated with mBC nationally | Younger women = 73,331,141.63 |
| Midlife women = 269,245,684.18 | |||||||
| Older women = 72,236,646.98 | |||||||
| 9 | Wendy Max [46] | 2001 | United State | – | Prevalence base | Premature death | 2,157,428,410.62 |
| 10 | Eric S.Meadows [57] | 2005 | United State | – | Incidence based | Morbidity | 6428.50 |
| 11 | Sonja V.Sorensen [50] | 2010 | United State | – | Incidence based | Premature death | 321,957,234.86 |
| Missed days’ work | 301,934,425.64 | ||||||
| Unpaid help | 54,773,302.74 | ||||||
| Total | 682,998,152.02 | ||||||
| 12 | de las.Heras [60] | 2016 | Spain | – | Incidence based | Total | 388.41 |
| 13 | Louisa Gordon [54] | 2005 | Australia | – | Not specified | Missed days’ work | 2494$ |
| Unpaid help | 435.56$ | ||||||
| Total | 3732.47 | ||||||
| 14 | Yin Wan [31] | Not specified | United State | – | Not specified | Morbidity | MBC = 6165.8 |
| EBC = 3689.7 | |||||||
| Missed days’ work | MBC = 1584 | ||||||
| EBC = 1015 | |||||||
| 15 | Alessandra Binazzi [53] | 2006 | Italy | – | Not specified | Value of work productivity lost | 71,767,637.28$ |
| 16 | Hafiz Zahid Mahmood [56] | 2015 | Pakistan | – | Not specified | Missed days’ work | 70.49 |
| Unpaid help | 21.61 | ||||||
| Total | 326.23 | ||||||
| 17 | Ravi K.Goyal [61] | 2015 | United State | – | Not specified | Total | 11,379.46 |
| 18 | Clement Ferrier [32] | Not specified | France | HC&FC | Not specified | Missed days’ work | 22,898.12(HC) |
| Per patient | |||||||
| 7571.43(FC) | |||||||
| Per patient | |||||||
| Total | 25,162.79(HC) | ||||||
| Per patient | |||||||
| 8553.71(FC) | |||||||
| Per patient | |||||||
| 19 | Rajabali Daroudi [10] | 2010 | Iran | HC | Prevalence base | Premature death | 226,544.05 |
| Missed days’ work | 6348.27 | ||||||
| 20 | Wesley Yin [59] | 2013 | United State | HC&FC | Not specified | Missed days’ work | Non-metastatic: 27,238.20 metastatic: 34,564.53 |
| 21 | Juan Oli va [47] | Not specified | Spain | HC&FC | Not specified | Premature death | 223,328.35 based on HCA and 4,518,628.55 based on FCA |
| Permanent disability | 314,671,039.50 based on HCA and 10,771,684.06 based on FCA | ||||||
| Total | 570,359,693.86 based on HCA and 22,956,005.13 based on FCA | ||||||
| 22 | Paul Hanly [39] | 2008 | Ireland | HC&FC | Not specified | Premature death | 108,419.60 based on HCA and 1488.61 based on FCA |
| Morbidity | 139,799.76 based on HCA and 8909.85 based on FCA | ||||||
| Missed days’ work | 63,566.23 based on HCA and 33.37 based on FCA | ||||||
| Total | 248,219.35 based on HCA and 10,398.46 based on FCA | ||||||
| 23 | KIM S.G [43] | 2002 | Korea | HC | Prevalence base | Premature death | 253,290,344.47 |
| Morbidity | 179,708,791.89 | ||||||
| 24 | Alison Pearce [48] | 2011–2030 | Ireland | HC | Incidence based | Premature death | 52,251,513,523.53 |
| Value of lost paid production | 1,772,314,850.60 | ||||||
| 25 | Cathy J. Bradley [33] | 2010 | United State | HC | Not specified | Premature death | 12,981,917,165.92 |
| Unpaid help | 308 billion | ||||||
| 26 | Paul Hanly [36] | 2008 | HC | Not specified | Premature death | 5,742,690,674.97 | |
| 27 | Kwang-Sig Lee [44] | 2010 | Korea | HC | Not specified | Premature death | 715,990,885.54 |
| Morbidity | 596,659,071.28 | ||||||
| 28 | Soheila Khorasani [42] | 2012 | Iran | HC | Not specified | Premature death | 171,960,573.41 |
| 29 | Behzad Karami-matin [41] | 2006–2010 | Iran | HC | Not specified | Premature death | 5698.01 in 2006, 6088.31 in 2007, 5777.21 in 2008, 5900.88 in 2009, 4546.44 in 2010 |
| 30 | Alicia C.Sasser [49] | 1998–2000 | United State | – | Not specified | Premature death | 6760.01 |
| Morbidity | 5338.09 | ||||||
| 31 | Ramon Luengo [34] | 2009 | European Union | – | Not specified | Unpaid help | 2,612,459,857.54 |
| Total | 2,653,279,542.82 | ||||||
| 32 | Rijo M John [62] | 2008 | Global | – | Not specified | Indirect cost | 88 billions |
| 33 | Anton Barchuk [37] | 2016 | Russia | HC | Incidence based | Premature death | 22,386 |