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Flow diagram of adults hospitalised with SARS-CoV-2 infection. Inclusion and exclusion criteria in the cohort stratified by the primary comparison or SARS-CoV-2 variant. Any patient may be excluded for multiple reasons at each stage, hence the counts of reasons for exclusion may not add up to the number of patients excluded. FiO2, fraction of inspired oxygen; LOS, length of stay; VOC, variant of concern; WHO, World Health Organisation.
