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. 2022 Dec 8;15:17562864221138147. doi: 10.1177/17562864221138147

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© The Author(s), 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — The effect of the combination of different emotional disorders and the number of comorbid emotional disorders on the QOL of people with epilepsy.

The stratified analysis showed that comorbid SSD and anxiety, comorbid SSD and depression, comorbid anxiety and depression, and comorbid SSD and anxiety and depression all had independent effects on QOL (all p < 0.001). In addition, their effect of reducing QOLIE-31 scores increased sequentially (β: –15.6 versus –21.3 versus –22.2 versus –23.0). One, two, and three comorbid emotional disorders, all had independent effects on the QOL of epilepsy people (all p < 0.001). Moreover, the effect on reducing the QOLIE-31 score was greater with the increasing number of comorbidities (β: –12.1 versus –20.7 versus –23.0).