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. 2022 Mar 31;9:821–824. doi: 10.1016/j.toxrep.2022.03.028

Table 2.

Effects of D-allulose administration on embryo or fetal developmenta.

Examination indicators (per litter unless noted otherwise) D-allulose administration Dose (mg/kg body weight)
0 1250 2500 5000
Number of corpora lutea 15.1 ± 2.1 15.7 ± 2.0 15.9 ± 2.2 14.1 ± 2.7
Number of implantations 14.8 ± 2.7 15.4 ± 1.9 15.7 ± 2.1 14.1 ± 2.6
Live fetuses
Number of live fetuses 14.6 ± 2.7 15.3 ± 2.0 15.6 ± 2.1 13.8 ± 2.7
Body length (mm) 36.0 ± 2.1 36.1 ± 1.6 35.9 ± 1.8 36.0 ± 1.9
Tail length (mm) 11.5 ± 1.0 11.5 ± 1.0 11.4 ± 1.0 11.4 ± 1.0
Body weight (g) 4.3 ± 0.5 4.4 ± 0.4 4.3 ± 0.4 4.4 ± 0.4
Sex ratio (female:male) 0.89 1.01 1.09 1.10
Resorbed fetuses
Total number of corpora lutea
Total number of litters
257
4
314
1
270
1
253
3
Total number of resorbed fetuses 5 1 1 5
Fetal resorption rate (%)b) 2.0 0.3 0.4 2.0

No statistically significant differences were noted among the groups when analyzed by the Anova or Dunnett method.

a

Examination indicators were enumerated on 17, 20, 17, and 18 dams with pregnancy confirmed for 0, 1250, 2500, and 5000 mg/kg body weight group, respectively.

b

) Fetal resorption rate was calculated through dividing the total number of resorbed fetuses by the total number of corpora lutea.