Table 2.
Biochemical parameters data by dosage group and sex during subchronic study.
| Biochemicals | Sex | Experimental groups |
|||
|---|---|---|---|---|---|
| Control | 559.36 mg/kg | 1118.72 mg/kg | 2237.44 mg/kg | ||
| ALP (IU/L) | F | 80.50 + 15.53 | 66.60 + 8.94 | 72.80 + 4.88 | 80.90 + 19.38 |
| M* | 80.10 + 7.59 | 86.20 + 4.82 | 86.80 + 6.13 | 89.60 + 4.51 | |
| ALT (IU/L) | F | 78.72 + 11.02 | 68.84 + 11.07 | 84.84 + 17.23 | 84.01 + 15.36 |
| M | 65.83 + 5.48 | 75.19 + 8.23 | 76.23 + 12.12 | 78.24 + 7.16 | |
| AST (IU/L) | F* | 135.15 + 17.42 | 146.30 + 9.42 | 151.10 + 12.80 | 167.48 + 5.69★ |
| M | 127.20 + 12.03 | 131.62 + 9.81 | 138.00 + 16.62 | 155.62 + 11.49✢ | |
| CK (IU/L) | F | 491.80 + 104.75 | 522.00 + 79.26 | 536.20 + 64.97 | 640.60 + 86.96★ |
| M | 544.60 + 28.87 | 567.00 + 70.30 | 570.40 + 65.42 | 694.20 + 93.03✢ | |
| LDH (U/L) | F | 1002.2 + 263.31 | 1091.2 + 77.51 | 1106.2 + 66.18 | 1249.4 + 77.41★ |
| M | 843.8 + 274.64 | 1090.4 + 90.06 | 1015.6 + 90.10 | 1262.2 + 186.81✢ | |
| TG (mg/DL) | F | 62.48 + 4.61 | 56.05 + 5.21 | 63.97 + 3.90 | 59.80 + 5.81 |
| M* | 64.74 + 8.95 | 63.74 + 3.47 | 62.82 + 6.00 | 61.64 + 3.87 | |
| HDLC (mg/DL) | F* | 49.21 + 0.72 | 47.17 + 3.98 | 50.86 + 2.57 | 52.45 + 6.34 |
| M | 36.46 + 2.30 | 39.46 + 2.38 | 37.54 + 1.34 | 38.24 + 0.87 | |
| Urea (mg/dl) | F* | 46.00 + 2.59 | 44.32 + 3.49 | 40.72 + 2.09 | 47.08 + 15.52 |
| M | 39.26 + 1.13 | 38.48 + 3.68 | 38.88 + 1.28 | 38.84 + 6.33 | |
| Uric acid (mg/dl) | F | 1.40 + 0.20 | 1.68 + 0.49 | 1.72 + 0.54 | 1.33 + 0.42 |
| M | 1.74 + 0.57 | 1.66 + 0.51 | 1.54 + 0.32 | 1.60 + 0.50 | |
| Creatinine (mg/dl) | F | 0.38 + 0.01 | 0.40 + 0.01 | 0.41 + 0.02 | 0.38 + 0.02 |
| M | 0.36 + 0.01 | 0.41 + 0.10 | 0.38 + 0.05 | 0.38 + 0.04 | |
| Albumin (mg/dL) | F* | 4.67 + 0.11 | 4.47 + 0.11 | 4.45 + 0.11 | 4.46 + 0.20 |
| M | 4.17 + 0.11 | 4.24 + 0.15 | 4.18 + 0.07 | 4.32 + 0.14 | |
| Glucose (mg/dl) | F | 168.51 + 6.36 | 180.45 + 5.77 | 171.25 + 7.03 | 162.25 + 32.60 |
| M | 180.47 + 25.24 | 167.66 + 6.38 | 165.27 + 14.70 | 161.60 + 4.82 | |
| Amylase (U/L) | F | 2391.6 + 135.57 | 2326.4 + 90.15 | 2324.2 + 92.33 | 2255.4 + 124.03 |
| M | 2218.4 + 73.61 | 2298.8 + 76.82 | 2319.6 + 107.66 | 2327.0 + 93.11 | |
| Total bilirubin (mg/dl) | F | 0.08 + 0.03 | 0.10 + 0.04 | 0.07 + 0.03 | 0.08 + 0.02 |
| M | 0.09 + 0.02 | 0.07 + 0.01 | 0.07 + 0.01 | 0.07 + 0.01 | |
| Total protein (mg/dL) | F* | 6.32 + 0.03 | 6.46 + 0.22 | 6.46 + 0.23 | 6.17 + 0.33 |
| M | 5.81 + 0.26 | 6.07 + 0.17 | 5.85 + 0.30 | 5.86 + 0.08 | |
| Total cholesterol (mg/DL) | F* | 55.50 + 4.28 | 57.53 + 5.30 | 57.53 + 5.10 | 51.41 + 6.65 |
| M | 45.46 + 2.69 | 44.53 + 3.27 | 43.46 + 2.31 | 42.62 + 1.08 | |
Values are presented as M + SD; One/two -way ANOVA followed by a Dennett’s post hoc test; P < 0.05 was considered statistically significant; *Significant p-value, between male and female groups; ✢Significant p-value, between control and treated groups of males; ★Significant p-value, between control and treated groups of females.