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. 2022 Jun 3;9:1291–1296. doi: 10.1016/j.toxrep.2022.05.021

Table 5.

Main test ear thickness measurements for vehicle, positive control and AGIQ concentrations of 10 %, 25 %, and 50 % (n = 5 per group).

Main test: ear thickness (mm)
Treatment Mean ear thickness
% Ear swelling
Day 1 Day 3 Day 6 Day 3–1 Day 6–1
N, N-Dimethylformamide (DMF) 0.18 0.18 0.19 0.0 5.6
25 % (v/v) HCA (Positive Control in DMF) 0.18 0.20 0.22 11.1 22.2
10 % AGIQ in DMF 0.18 0.19 0.19 5.6 5.6
25 % AGIQ in DMF 0.18 0.18 0.19 0.0 5.6
50 % (w/v) AGIQ in DMF 0.17 0.18 0.19 5.9 11.8