Table 2.
Effect of the enriched fraction on body weight, food intake and water intake on BALB/c mice.
| Parameters | Sub- acute toxicity |
Acute toxicity |
|||||
|---|---|---|---|---|---|---|---|
| Control | 50 mg/Kg bw | 500 mg/Kg bw | Control | 200 mg/Kg bw | 800 mg/Kg bw | 1600 mg/Kg bw | |
| Female | |||||||
| Initial weight | 18.62 ± 0.35 | 17.74 ± 0.18 | 18.76 ± 0.33 | 15.42 ± 0.36 | 18.13 ± 0.59 | 16.07 ± 0.26 | 18.57 ± 0.21 |
| Day 4 (g) | – | – | – | 16.7 ± 0.24 | 18.8 ± 0.37 | 16.6 ± 0.47 | 19.05 ± 0.05 |
| Day 7 (g) | 18.64 ± 0.38 | 17.9 ± 0.13 | 19.02 ± 0.23 | 16.75 ± 0.34 | 19 ± 0.61 | 16.95 ± 0.37 | 19.55 ± 0.25 |
| Day 14 (g) | 19.34 ± 0.39 | 18.52 ± 0.17 | 19.76 ± 0.31 | – | – | – | – |
| Food intake (g/day/mice) | 3.21 ± 0.06 | 2.84 ± 0.09 | 2.79 ± 0.13 | 2.72 ± 0.1 | 3.01 ± 0.2 | 2.74 ± 0.26 | 3.07 ± 0.26 |
| Water intake (ml/day/mice) | 3.58 ± 0.11 | 3.15 ± 0.10 | 3.23 ± 0.11 | 3.41 ± 0.09 | 3.83 ± 0.25 | 3.2 ± 0.15 | 3.67 ± 0.09 |
| Male | |||||||
| Initial weight | 21.76 ± 0.46 | 20.28 ± 0.21 | 21.66 ± 0.44 | – | – | – | – |
| Day 7 (g) | 22.38 ± 0.48 | 20.82 ± 0.28 | 22.89 ± 0.35 | – | – | – | – |
| Day 14 (g) | 23.98 ± 0.41 | 22.38 ± 0.19 | 23.06 ± 0.47 | – | – | – | – |
| Food intake (g/day/mice) | 3.43 ± 0.12 | 3.40 ± 0.10 | 3.29 ± 0.13 | – | – | – | – |
| Water intake (ml/day/mice) | 4.32 ± 0.15 | 4.30 ± 0.19 | 3.97 ± 0.12 | – | – | – | – |
Values are expressed as mean ± SEM. p > 0.05 when compared to normal control group.