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. 2022 May 17;9:1142–1149. doi: 10.1016/j.toxrep.2022.05.007

Table 2.

Effect of the enriched fraction on body weight, food intake and water intake on BALB/c mice.

Parameters Sub- acute toxicity
Acute toxicity
Control 50 mg/Kg bw 500 mg/Kg bw Control 200 mg/Kg bw 800 mg/Kg bw 1600 mg/Kg bw
Female
Initial weight 18.62 ± 0.35 17.74 ± 0.18 18.76 ± 0.33 15.42 ± 0.36 18.13 ± 0.59 16.07 ± 0.26 18.57 ± 0.21
Day 4 (g) 16.7 ± 0.24 18.8 ± 0.37 16.6 ± 0.47 19.05 ± 0.05
Day 7 (g) 18.64 ± 0.38 17.9 ± 0.13 19.02 ± 0.23 16.75 ± 0.34 19 ± 0.61 16.95 ± 0.37 19.55 ± 0.25
Day 14 (g) 19.34 ± 0.39 18.52 ± 0.17 19.76 ± 0.31
Food intake (g/day/mice) 3.21 ± 0.06 2.84 ± 0.09 2.79 ± 0.13 2.72 ± 0.1 3.01 ± 0.2 2.74 ± 0.26 3.07 ± 0.26
Water intake (ml/day/mice) 3.58 ± 0.11 3.15 ± 0.10 3.23 ± 0.11 3.41 ± 0.09 3.83 ± 0.25 3.2 ± 0.15 3.67 ± 0.09
Male
Initial weight 21.76 ± 0.46 20.28 ± 0.21 21.66 ± 0.44
Day 7 (g) 22.38 ± 0.48 20.82 ± 0.28 22.89 ± 0.35
Day 14 (g) 23.98 ± 0.41 22.38 ± 0.19 23.06 ± 0.47
Food intake (g/day/mice) 3.43 ± 0.12 3.40 ± 0.10 3.29 ± 0.13
Water intake (ml/day/mice) 4.32 ± 0.15 4.30 ± 0.19 3.97 ± 0.12

Values are expressed as mean ± SEM. p > 0.05 when compared to normal control group.