Table 2.
Results of the biochemical analysis for rats (n = 10; mean value ± S.D.).
| Parameter | 0 mg/kg |
250 mg/kg |
500 mg/kg |
1000 mg/kg |
||||
|---|---|---|---|---|---|---|---|---|
| Male | Female | Male | Female | Male | Female | Male | Female | |
| Glucose (mg/dL) | 119.41 ± 14.41 | 120.98 ± 14.69 | 115.37 ± 16.27 | 117.32 ± 17.66 | 118.99 ± 12.30 | 120.97 ± 23.20 | 124.30 ± 12.66 | 109.24 ± 18.14 |
| Total cholesterol (mg/dL) | 104.60 ± 19.49 | 85.37 ± 12.10 | 92.60 ± 15.08 | 81.86 ± 14.57 | 96.80 ± 16.92 | 79.91 ± 9.01 | 97.40 ± 11.72 | 88.18 ± 21.46 |
| Triglycerides (mg/dL) | 80.80 ± 21.91 | 42.83 ± 9.45 | 84.63 ± 43.97 | 40.60 ± 7.74 | 73.03 ± 21.21 | 47.67 ± 8.99 | 69.07 ± 29.71 | 43.23 ± 8.02 |
| Creatinine (mg/dL) | 0.65 ± 0.08 | 0.63 ± 0.04 | 0.64 ± 0.06 | 0.67 ± 0.05 | 0.64 ± 0.04 | 0.64 ± 0.03 | 0.66 ± 0.07 | 0.64 ± 0.04 |
| γ-GT (U/L) | 0.98 ± 1.18 | 0.32 ± 0.35 | 0.72 ± 0.62 | 1.30 ± 2.04 | 1.63 ± 3.43 | 0.52 ± 0.49 | 1.35 ± 1.35 | 0.69 ± 0.42 * |
| ALP (U/L) | 82.23 ± 16.90 | 31.24 ± 3.18 | 89.35 ± 14.23 | 36.43 ± 11.27 | 80.34 ± 10.20 | 40.69 ± 21.40 | 83.44 ± 17.56 | 35.63 ± 13.78 |
| ALT (U/L) | 57.89 ± 20.35 | 31.45 ± 5.41 | 61.87 ± 13.84 | 32.32 ± 6.61 | 67.78 ± 18.05 | 33.67 ± 6.19 | 56.64 ± 9.38 | 38.99 ± 8.52 |
| AST (U/L) | 133.66 ± 29.77 | 101.13 ± 13.83 | 127.31 ± 29.17 | 112.66 ± 34.18 | 124.87 ± 41.38 | 96.66 ± 20.66 | 139.31 ± 46.34 | 113.38 ± 21.69 |
| Calcium (mg/dL) | 10.86 ± 0.38 | 10.72 ± 0.18 | 10.71 ± 0.16 | 10.69 ± 0.22 | 10.85 ± 0.42 | 10.37 ± 0.68 | 10.86 ± 0.21 | 10.73 ± 0.45 |
| Phosphorus (mg/dL) | 5.44 ± 0.62 | 4.61 ± 0.73 | 5.75 ± 0.83 | 5.05 ± 0.82 | 5.48 ± 0.51 | 4.45 ± 0.66 | 5.66 ± 0.49 | 4.90 ± 1.11 |
| Total protein (g/dL) | 6.71 ± 0.27 | 7.00 ± 0.25 | 6.79 ± 0.28 | 6.89 ± 0.29 | 6.94 ± 0.32 | 6.94 ± 0.47 | 6.91 ± 0.24 | 7.17 ± 0.37 |
| Albumin (g/dL) | 3.92 ± 0.14 | 4.21 ± 0.10 | 3.88 ± 0.12 | 4.10 ± 0.22 | 3.96 ± 0.15 | 4.13 ± 0.35 | 3.94 ± 0.11 | 4.24 ± 0.23 |
| Globulin (g/dL) | 2.79 ± 0.18 | 2.79 ± 0.22 | 2.91 ± 0.17 | 2.79 ± 0.12 | 2.98 ± 0.18 | 2.81 ± 0.16 | 2.96 ± 0.17 | 2.93 ± 0.16 |
| A/G | 1.41 ± 0.07 | 1.52 ± 0.12 | 1.34 ± 0.04 * | 1.47 ± 0.07 | 1.33 ± 0.05 * | 1.47 ± 0.09 | 1.33 ± 0.07 * | 1.45 ± 0.06 |
| Urea (mg/dL) | 37.17 ± 4.29 | 43.04 ± 6.31 | 37.02 ± 5.43 | 48.91 ± 7.95 | 39.29 ± 3.96 | 44.98 ± 4.93 | 39.19 ± 4.89 | 45.24 ± 6.07 |
| BUN (mg/dL) | 17.36 ± 2.00 | 20.10 ± 2.94 | 17.29 ± 2.54 | 22.84 ± 3.71 | 18.35 ± 1.85 | 21.01 ± 2.30 | 18.30 ± 2.28 | 21.13 ± 2.84 |
| Total bilirubin (μmol/L) | 0.78 ± 0.34 | 0.58 ± 0.55 | 0.77 ± 0.18 | 0.84 ± 0.58 | 0.85 ± 0.22 | 0.57 ± 0.39 | 0.72 ± 0.32 | 0.29 ± 0.27 |
| HDL-C (mg/dL) | 19.63 ± 1.06 | 18.55 ± 2.99 | 17.83 ± 2.22 | 18.25 ± 3.20 | 18.42 ± 2.30 | 17.45 ± 2.09 | 18.19 ± 2.26 | 19.33 ± 5.06 |
| LDL-C (mg/dL) | 3.20 ± 1.06 | 2.91 ± 0.81 | 3.46 ± 1.58 | 3.17 ± 1.06 | 3.60 ± 0.89 | 3.62 ± 1.29 | 1.88 ± 0.15 | 3.23 ± 1.17 |
| Sodium (meq/L) | 144.54 ± 0.84 | 142.79 ± 0.61 | 144.21 ± 1.54 | 142.96 ± 1.11 | 144.13 ± 1.11 | 143.04 ± 1.39 | 147.10 ± 1.60 | 143.50 ± 0.91 |
| Potassium (meq/L) | 4.43 ± 0.22 | 4.29 ± 0.29 | 4.41 ± 0.22 | 4.25 ± 0.42 | 4.38 ± 0.25 | 4.18 ± 0.28 | 8.59 ± 1.49 * | 4.34 ± 0.34 |
| Chloride (meq/L) | 109.10 ± 1.11 | 107.69 ± 1.12 | 108.35 ± 1.47 | 108.01 ± 2.04 | 108.19 ± 0.99 | 107.72 ± 2.18 | 99.70 ± 1.49 | 108.62 ± 1.36 |
γ-GT, γ-glutamyltransferase; ALP, alkaline phosphatase; AST, aspartate transaminase; ALT, alanine aminotransferase; A/G, albumin/globulin; BUN, blood urea nitrogen; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. * p < 0.05; significance compared to the control group.