Table 4.
0 mg/kg |
250 mg/kg |
500 mg/kg |
1000 mg/kg |
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Organ | Absolute organ weight (g) | Relative organ weight (%) | Absolute organ weight (g) | Relative organ weight (%) | Absolute organ weight (g) | Relative organ weight (%) | Absolute organ weight (g) | Relative organ weight (%) | |
Male | Liver | 11.624 ± 0.681 | 2.649 ± 0.124 | 11.688 ± 1.543 | 2.662 ± 0.177 | 11.167 ± 1.249 | 2.668 ± 0.164 | 11.733 ± 1.267 | 2.664 ± 0.246 |
Heart | 1.178 ± 0.089 | 0.269 ± 0.024 | 1.167 ± 0.088 | 0.267 ± 0.019 | 1.133 ± 0.104 | 0.271 ± 0.012 | 1.165 ± 0.121 | 0.264 ± 0.021 | |
Spleen | 0.632 ± 0.078 | 0.144 ± 0.014 | 0.622 ± 0.086 | 0.142 ± 0.014 | 0.621 ± 0.084 | 0.149 ± 0.019 | 0.664 ± 0.087 | 0.151 ± 0.016 | |
Brain | 2.151 ± 0.109 | 0.491 ± 0.035 | 2.105 ± 0.092 | 0.482 ± 0.032 | 2.080 ± 0.109 | 0.499 ± 0.030 | 2.104 ± 0.110 | 0.478 ± 0.023 | |
Thymus | 0.289 ± 0.059 | 0.066 ± 0.013 | 0.351 ± 0.084 | 0.080 ± 0.015 | 0.297 ± 0.040 | 0.071 ± 0.010 | 0.349 ± 0.062 | 0.080 ± 0.016 | |
Kidneys | 2.327 ± 0.225 | 0.529 ± 0.0.34 | 2.333 ± 0.202 | 0.533 ± 0.032 | 2.223 ± 0.182 | 0.532 ± 0.024 | 2.357 ± 0.247 | 0.536 ± 0.056 | |
Adrenals | 0.065 ± 0.005 | 0.015 ± 0.001 | 0.067 ± 0.012 | 0.015 ± 0.002 | 0.066 ± 0.008 | 0.016 ± 0.002 | 0.067 ± 0.010 | 0.015 ± 0.003 | |
Testes | 4.035 ± 0.325 | 0.919 ± 0.069 | 3.863 ± 0.252 | 0.885 ± 0.072 | 3.983 ± 0.337 | 0.958 ± 0.102 | 3.960 ± 0.529 | 0.898 ± 0.100 | |
Epididymides | 1.322 ± 0.099 | 0.301 ± 0.019 | 1.299 ± 0.120 | 0.297 ± 0.024 | 1.286 ± 0.072 | 0.309 ± 0.025 | 1.225 ± 0.193 | 0.278 ± 0.039 | |
Seminal vesicles with coagulating glands and prostate | 2.184 ± 0.388 | 0.495 ± 0.069 | 2.291 ± 0.403 | 0.522 ± 0.073 | 2.309 ± 0.259 | 0.554 ± 0.065 | 2.349 ± 0.312 | 0.533 ± 0.059 | |
Thyroid with parathyroid | 0.0216 ± 0.0029 | 0.0049 ± 0.0005 | 0.0234 ± 0.0038 | 0.0053 ± 0.0007 | 0.0216 ± 0.0025 | 0.0052 ± 0.0007 | 0.0254 ± 0.0029a | 0.0058 ± 0.0009 | |
Pituitary gland | 0.0104 ± 0.0016 | 0.0024 ± 0.0003 | 0.0104 ± 0.0018 | 0.0024 ± 0.0003 | 0.0102 ± 0.0012 | 0.0025 ± 0.0002 | 0.0107 ± 0.0016 | 0.0024 ± 0.0003 | |
Female | Liver | 7.015 ± 0.404 | 2.856 ± 0.267 | 7.305 ± 0.520 | 2.929 ± 0.252 | 7.157 ± 0.919 | 2.880 ± 0.173 | 7.174 ± 0.617 | 2.927 ± 0.200 |
Heart | 0.836 ± 0.038 | 0.340 ± 0.017 | 0.837 ± 0.068 | 0.335 ± 0.028 | 0.848 ± 0.072 | 0.343 ± 0.032 | 0.820 ± 0.058 | 0.335 ± 0.020 | |
Spleen | 0.440 ± 0.039 | 0.179 ± 0.021 | 0.454 ± 0.042 | 0.182 ± 0.020 | 0.450 ± 0.063 | 0.182 ± 0.026 | 0.425 ± 0.055 | 0.174 ± 0.023 | |
Brain | 1.969 ± 0.073 | 0.801 ± 0.055 | 1.981 ± 0.048 | 0.794 ± 0.044 | 1.916 ± 0.114 | 0.776 ± 0.064 | 1.907 ± 0.083 | 0.780 ± 0.048 | |
Thymus | 0.308 ± 0.033 | 0.125 ± 0.011 | 0.337 ± 0.073 | 0.135 ± 0.028 | 0.326 ± 0.064 | 0.132 ± 0.027 | 0.303 ± 0.054 | 0.123 ± 0.020 | |
Kidneys | 1.552 ± 0.076 | 0.631 ± 0.033 | 1.587 ± 0.075 | 0.636 ± 0.045 | 1.514 ± 0.144 | 0.611 ± 0.038 | 1.507 ± 0.093 | 0.615 ± 0.040 | |
Adrenals | 0.076 ± 0.009 | 0.031 ± 0.005 | 0.081 ± 0.004 | 0.033 ± 0.003 | 0.080 ± 0.014 | 0.032 ± 0.004 | 0.078 ± 0.009 | 0.032 ± 0.003 | |
Ovaries | 0.089 ± 0.010 | 0.036 ± 0.005 | 0.095 ± 0.022 | 0.038 ± 0.008 | 0.104 ± 0.011 | 0.042 ± 0.003 | 0.092 ± 0.017 | 0.038 ± 0.006 | |
Uterus with cervix | 0.628 ± 0.130 | 0.255 ± 0.049 | 0.708 ± 0.114 | 0.284 ± 0.049 | 0.742 ± 0.166 | 0.304 ± 0.084 | 0.641 ± 0.151 | 0.262 ± 0.064 | |
Thyroid with parathyroid | 0.0159 ± 0.0019 | 0.0065 ± 0.0007 | 0.0165 ± 0.0023 | 0.0066 ± 0.0011 | 0.0166 ± 0.0026 | 0.0067 ± 0.0011 | 0.0149 ± 0.0015 | 0.0061 ± 0.0009 | |
Pituitary gland | 0.0164 ± 0.0020 | 0.0067 ± 0.0010 | 0.0159 ± 0.0022 | 0.0064 ± 0.0010 | 0.0150 ± 0.0016 | 0.0061 ± 0.0008 | 1.0151 ± 0.0020 | 0.0062 ± 0.0008 |
p < 0.05; significant compared to the control group.