Table 5.
Risk evaluation for AFM1 via consumption of raw cow milk.
| Region | Age category | Av.body Wgt. (kg) | Estimated Daily Intake (EDI) (ng/ kgbw/day) | MOE | Cancer Risk (Cases/100,000 person/yr) |
|---|---|---|---|---|---|
| Greater Accra |
Infants (0–11mths) |
2.9 | 0.61 | 655.74 | 0.02 |
| Toddlers (12–35mths) | 9.8 | 0.36 | 1111.11 | 0.01 | |
| Children (36mths-10yrs) |
26 | 0.14 | 2857.14 | 4.5 × 10-3 | |
| Adolescents (11–17 yrs) |
46.25 | 0.08 | 5000.00 | 2.58 × 10-3 | |
| Adults (18–64 yrs) |
60.7 | 0.06 | 6666.67 | 1.94 × 10-3 | |
| Volta | Infants (0–11mths) |
2.9 | 1.28 | 312.50 | 0.04 |
| Toddler (12–35mths) | 9.8 | 0.75 | 533.33 | 0.02 | |
| Children (36mths-11yrs) |
26 | 0.29 | 1379.31 | 9.37 × 10-3 | |
| Adolescents (11–17 yrs) |
46.25 | 0.16 | 2500.00 | 5.17 × 10-3 | |
| Adults (18–64 yrs) |
60.7 | 0.12 | 3333.33 | 3.88 × 10-3 | |
| Western | Infants (0–11mths) |
2.9 | 2.03 | 197.04 | 0.07 |
| Toddlers (12–35mths) | 9.8 | 1.20 | 333.33 | 0.04 | |
| Children (36mths-10yrs) |
26 | 0.45 | 888.89 | 0.014 | |
| Adolescents (11–17 yrs) |
46.3 | 0.25 | 1600.00 | 8.08 × 10-3 | |
| Adults (18–64 yrs) |
60.7 | 0.19 | 2105.26 | 6.14 × 10-3 | |
| Eastern | Infants (0–11mths) |
2.9 | 1.58 | 253.16 | 0.05 |
| Toddlers (12–35mths) | 9.8 | 0.94 | 425.53 | 0.03 | |
| Children (36mths-10yrs) |
26 | 0.35 | 1142.85 | 0.01 | |
| Adolescents (11–17 yrs) |
46.3 | 0.20 | 2000.00 | 6.46 × 10-3 | |
| Adults (18–64 yrs) |
60.7 | 0.15 | 2666.67 | 4.85 × 10-3 |
Margin of Exposure-MOE
Mean of AFM1- GTA= 0.26 µg/kg, VR= 0.54 µg/kg
Daily intake of milk for infants was halved (0.5 ×0.0137 kg)
Average potency of aflatoxin= 0.0323
Average Body weights were obtained from the different ranges referenced by the authors 1 µg= 1000 ng
1 µg= 1000 ng
Means of AFM1- WR-0.86 µg/kg, ER- 0.67 µg/kg.