Table 2.
Body weights and clinical observations in mice treated with damnacanthal during acute oral toxicity study.
| Group | Dose (mg/kg) | No. dosed | Body weight (g)a |
Symptom observation (no. animal) | No. death | ||
|---|---|---|---|---|---|---|---|
| Day 0 | Day 7 | Day 14 | |||||
| I | Control | 1 | 39.50 | 39.12 | 40.30 | Not found | 0 |
| II | 300 | 3 + 3 | 38.04 ± 2.12 | 37.72 ± 2.38 | 38.63 ± 3.30 | Mild watery diarrhea (n = 2) | 0 |
| III | 2000 | 3 + 3 | 38.04 ± 1.95 | 38.92 ± 4.03 | 40.35 ± 3.69 | Moderate watery diarrhea (n = 5) | 1 |
| Severe dehydration (n = 1) | |||||||
a
Values are the mean ± SD (n = 5–6) except for a control group.