Table 3.
Serum biochemistry parameters of tumor-bearing nude mice on day 26 after treatment with vehicle only (negative control, NC), 5-FU at 20 mg/kg (F20), or damnacanthal at 20 mg/kg (D20) or 40 mg/kg (D40).
| Parameters | Value of serum biochemistrya |
|||
|---|---|---|---|---|
| NC | F20 | D20 | D40 | |
| ALT (U/L) | 34 ± 5 | 33 ± 5 | 30 ± 3 | 31 ± 6 |
| AST (U/L) | 114 ± 38 | 87 ± 21 | 91 ± 36 | 76 ± 17 |
| Creatinine (mg/dL) | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 |
| BUN (mg/dL) | 25 ± 2 | 28 ± 9 | 23 ± 3 | 23 ± 4 |
ALT: alanine aminotransferase, AST: aspartate aminotransferase, BUN: blood urea nitrogen.
a
Values are the mean ± SD (n = 6).