Table 3.
Key Pathway Advisor pathway predictions for adjuvants. Analysis based on the input of differentially expressed proteins (p = 0.05) induced by exposure of the DC model to the indicated adjuvants against controls. In brackets: total number of pathways predicted.
| Pathway associated with | BEN (87) | NND (40) | POL (6) |
|---|---|---|---|
| Fatty acid, lipid, and cholesterol metabolism/homeostasis | – | – | 5 |
| Other metabolism | 1 | 2 | – |
| ER stress | – | – | 1 |
| Chemotaxis/cell adhesion/cytoskeletal re-arrangements | 4 | – | – |
| Oxidative stress: ROS-induced cellular signaling | 1 | – | – |
| DNA damage | 2 | – | – |
| NF-ΚB-associated signaling | 5 | – | – |
| Specific signal transduction | 9 | 5 | – |
| Number of cytokine and immune response-associated pathways | 18 | 2 | 0 |