Table 2.

Accuracy of detecting severe traumatic brain injury.

	AUC	95% CI	p value	Optimal cut-off value	Se (%)	Sp (%)	PPV(%)	NPV(%)
GFAP	0.810	0.712–0.881	<0.0001	947 pg/mL	75.6	78.3	50.8	91.5
S100β	0.476	0.377–0.577	0.908	485 pg/mL	26.8	79.7	28.2	78.6

GFAP, gilial fibrillary acidic protein; AUC, area under the curve; CI, confidence interval; Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value.