Table 2.
Unadjusted Posttransplant Outcomes
| Outcomes | Total (N=807) | AGVHD grade 0-I (N=615) | AGVHD grade III-IV (N=192) | P-value1 |
|---|---|---|---|---|
| Relapsed after 1 year post-HCT | 0.02 | |||
| No | 734 (91.0%) | 551 (89.6%) | 183 (95.3%) | |
| Yes | 73 (9.0%) | 64 (10.4%) | 9 (4.7%) | |
| Chronic GVHD | 0.17 | |||
| No | 329 (41.3%) | 259 (42.7%) | 70 (37.0%) | |
| Yes | 467 (58.7%) | 348 (57.3%) | 119 (63.0%) | |
| Missing | [N=11] | [N=8] | [N=3] | |
| SF-12 PCS, mean (STD) | 45.2 (10.8) | 45.9 (10.5) | 42.5 (11.8) | 0.01 |
| SF-12 MCS, mean (STD) | 51.6 (9.1) | 52.0 (8.7) | 49.7 (10.6) | 0.04 |
| Missing | [N=386] | [N=273] | [N=113] | |
| Overall health | ||||
| Poor, Fair | 64 (14.8%) | 44 (12.5%) | 20 (24.7%) | 0.005 |
| Good, Very Good, Excellent | 370 (85.2%) | 309 (87.5%) | 61 (75.3%) | |
| Missing | [N=373] | [N=262] | [N=111] | |
| KPS | ||||
| <80 | 61 (14.4%) | 41 (11.9%) | 20 (25.6%) | 0.002 |
| 80+ | 362 (85.6%) | 304 (88.1%) | 58 (74.4%) | |
| Missing | [N=384] | [N=270] | [N=114] | |
| Died after 1 year post-HCT | 0.02 | |||
| No | 609 (75.5%) | 476 (77.4%) | 133 (69.3%) | |
| Yes | 198 (24.5%) | 139 (22.6%) | 59 (30.7%) | |
| Follow up years among survivors | ||||
| Median (IQR) | 7.2 (3.4–13.0) | 7.3 (3.7–13.1) | 6.3 (2.5–12.0) | 0.06 |
HCT, hematopoietic stem cell transplant; GVHD, graft-versus-host disease; SF-12, short form survey 12; PCS, physical component summary; MCS, mental component summary; STD, standard deviation; KPS, Karnofsky performance scale; IQR, interquartile range
1
based on the Chi-square test for categorical variables, the T-test where means are reported, and the Wilcoxon rank sum test where medians are reported