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. 2022 Dec 12;12:21458. doi: 10.1038/s41598-022-25892-x

Table 7.

Factors associated with infant’s death using univariate and multivariate logistic regression models.

Characteristics Univariate Multivariate
Crude OR [95% CI] p value Adjusted OR [95% CI] p value
Gravidity 1.42 [0.59;3.41] 0.437 –
IPT 0.46 [0.17;1.21] 0.116 –
Maternal fever 1.52 [0.70;3.31] 0.293 –
Maternal infection 1.34 [0.44;4.08] 0.609 –
PROM 1.27 [0.59;2.72] 0.539 –
Abnormal amniotic fluid 0.38 [0.17;0.83] 0.015 –
Apgar at 1 min > 7 0.26 [0.12;0.59] 0.001 –
Apgar at 5 min > 7 0.15 [0.06;0.42]  < 0.001 –
Skin mottling 43.6 [8.58;221.56]  < 0.001 55.5 [3.67;838.97] 0.004
Sex 0.67 [0.32;1.41] 0.290 –
Preterm birth 5.87 [2.53;13.58]  < 0.001 –
Low birthweight 6.43 [2.77;14.91]  < 0.001 4.32 [1.11;16.80] 0.035
Tachycardia (> 160 bpm) 2.43 [0.97;6.10] 0.058 –
CD74 0.67 [0.56;0.80]  < 0.001 0.72 [0.61;0.86]  < 0.001
CX3CR1 0.82 [0.25;2.64] 0.740 0.94 [0.20;4.32] 0.934
CXCL10 (pg/ml) 1.09 [0.99;1.19] 0.074 1.12 [0.99;1.27] 0.071
IL10 (pg/ml) 0.95 [0.35;2.56] 0.920 0.38 [0.03;4.16] 0.429
IL6 (pg/ml) 1.03 [0.95;1.12] 0.421 0.96 [0.83;1.10] 0.421
PCT (pg/ml) 1.11 [1.02;1.20] 0.015 1.10 [0.98;1.23] 0.076

IPT, intermittent preventive treatment against malaria; CD74, HLA class II histocompatibility antigen gamma chain; CX3CR1; CX3C chemokine receptor 1; IL, Interleukin; PCT, procalcitonin.

CD74 and CX3CR1 are expressed as relative expression to HPRT1.