Fig. 7. Gross and pulmonary histopathology of intranasally (IN) or eye-drop (ED)-infected wild-type Syrian hamsters.

Syrian hamsters were IN- or ED-infected with 10⁴ PFU of SARS-CoV-2 (each n = 5 for IN-mock-infected, IN-infected, ED-mock-infected, and ED-infected) a Representative digital image of lungs harvested from mock-infected or infected hamsters at 6 dpi. b Representative H&E stained lung tissue slices of mock-infected or infected hamsters at 6 dpi used to identify histopathological changes. The left panels represent low-magnification images (scale bar = 500 μm). The right panels show high-magnification images of the regions designated by squares (scale bar = 100 μm).