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. 2022 Nov 11;16:100498. doi: 10.1016/j.fochx.2022.100498

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 6 — Evaluation of anti-cancer activity of water-soluble IHFM on MCF-7, HepG-2, and MDA-MB-231 cells. (A) Water-soluble melanin can affect the vitality of MCF-7 cells. When water-soluble IHFM was used to treat MCF, the concentration of 1.413 mg/mL can reached the half-lethal rate. (B) The median lethal concentration of water-soluble IHFM treatment of HepG-2 was IC₅₀ = 4.99 mg/mL. (D) The Effect of water-soluble IHFM on the viability of MDA-MB-231 cells. Note: Different lowercase letters indicated significant difference between groups (p < 0.05).