Table 3.
Association between time-to-pregnancy (TTP) and risk of postpartum depression (PPD) stratified by history of anxiety or depression/postpartum depression
| History of anxiety or depression/postpartum depression | ||||
|---|---|---|---|---|
| Time-to-pregnancy (cycles) | # Women with PPD (%) | Total women | Crude risk ratio (95% CI) | Adjusted risk ratio* (95% CI) |
| <3 | 33 (15.3) | 216 | Ref | Ref |
| 3–5 | 59 (16.3) | 362 | 1.07 (0.72–1.57) | 1.02 (0.69–1.51) |
| 6–11 | 64 (20.3) | 315 | 1.33 (0.91–1.95) | 1.23 (0.84–1.81) |
| ≥12 | 22 (27.5) | 80 | 1.80 (1.23–2.89) | 1.55 (0.95–2.53) |
| No history of anxiety or depression/postpartum depression | ||||
| Time-to-pregnancy (cycles) | # Women with PPD (%) | Total women | Crude risk ratio (95% CI) | Adjusted risk ratio* (95%CI) |
| <3 | 20 (5.3) | 381 | Ref | Ref |
| 3–5 | 42 (6.2) | 678 | 1.18 (0.70–1.98) | 1.13 (0.67–1.93) |
| 6–11 | 36 (7.5) | 483 | 1.42 (0.84–2.41) | 1.29 (0.75–2.24) |
| ≥12 | 6 (4.7) | 128 | 0.89 (0.37–2.17) | 0.76 (0.32–1.84) |
Adjusted for age, history of subfertility/infertility, parity, preconception primary care physician visits, race/ethnicity, income, employment, use of fertility treatment to conceive, BMI.