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. 2022 Dec 9;12(12):e059666. doi: 10.1136/bmjopen-2021-059666

Table 4.

Comparison 1: diet and physical activity interventions versus usual care (additional outcomes)

Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI)
Participants, n
(studies)
Certainty of the evidence
(GRADE)
Risk with usual care Risk with diet+physical
BMI (kg/m2) The mean BMI was 24.75 kg/m2. Mean 1.07 kg/m2 lower
(from 1.27 lower to 0.88 lower)
871
(3 RCTs)
⊕⊕⊕⊕High
Weight change (kg) The mean weight was 70.45 kg. Mean 2.72 kg lower
(from 3.17 lower to 2.27 lower)
814
(3 RCTs)
⊕⊕⊕⊕High
Waist circumference (cm) The mean waist circumference was 94.43 cm. MD 3.07 cm lower
(from 5.15 lower to 0.98 lower)
451
(3 RCTs)
⊕⊕⊕◯
Moderate†
FPG (mmol/L) The mean FPG was 6.55 mmol/L. MD 0.77 mmol/L lower
(from 1.2 lower to 0.35 lower)
331
(2 RCTs)
⊕⊕⊕◯
Moderate†

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

†OIS not met.

BMI, body mass index; CI, confidence interval; FPG, fasting plasma glucose; MD, mean difference; RCT, randomised controlled trial.