Table 7.
Comparison 3: physical activity versus usual care (main outcomes)
| Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) |
Participants, n (studies) |
Certainty of the evidence (GRADE) |
|
| Risk with (usual care) | Risk with (physical activity) | ||||
| SBP (mm Hg) | The mean SBP was 145.8 mm Hg. | MD 9.7 mm Hg lower (from 11.05 lower to 8.35 lower) |
– | 103 (2 RCTs) |
⊕⊕⊕◯ Moderate† |
| DBP (mm Hg) | The mean DBP was 93.1 mm Hg. | MD 7.29 mm Hg lower (from 8.42 lower to 6.16 lower) |
– | 103 (2 RCTs) |
⊕⊕⊕◯ Moderate† |
| HDLc (mmol/L) | The mean HDL was 1.17 mmol/L. | MD 0.08 mmol/L higher (from 0.04 higher to 0.11 higher) |
– | 183 (2 RCTs) |
⊕⊕⊕◯ Moderate† |
| LDLc (mmol/L) | The mean LDL was 2.73 mmol/L | MD 0.02 mmol/L lower (from 0.1 lower to 0.05 higher) |
– | 183 (2 RCTs) |
⊕⊕◯◯ Low†‡ |
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
†OIS not met.
‡I2statistitc =77%, p=0.01, implying significant heterogeneity between studies without a lot of overlap in CIs.
CI, confidence interval; DBP, diastolic blood pressure; HDLc, high-density lipoprotein; LDLc, low-density lipoprotein; MD, mean difference; RCT, randomised condtrolled trial; SBP, systolic blood pressure.