Table 3. Contingency Table Describing the Correlation between Inhibitory Activity in Any of the Enzymatic Inhibition Assays and Thiol Reactivity for Our Library of Thiazoles and Thiadiazolesa.
thiol
reactivity |
||
---|---|---|
reactive | not reactive | |
inhibitory activity | 16 | 10 |
no inhibitory activity | 3 | 20 |
Most of the reactive compounds showed inhibitory activity.