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. 2022 Nov 3;13(12):1905–1910. doi: 10.1021/acsmedchemlett.2c00429

Table 3. Contingency Table Describing the Correlation between Inhibitory Activity in Any of the Enzymatic Inhibition Assays and Thiol Reactivity for Our Library of Thiazoles and Thiadiazolesa.

  thiol reactivity
  reactive not reactive
inhibitory activity 16 10
no inhibitory activity 3 20
a

Most of the reactive compounds showed inhibitory activity.