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| compd | Grp94 IC50 (μM)a | selectivity > Grp94 | Trap1 IC50 (μM)a | selectivity > Trap1 |
|---|---|---|---|---|
| 2 | 95.40 ± 4.61 | ∼159-fold | >100 | >166-fold |
| 23d | 6.60 ± 0.63 | ∼26-fold | >100 | >400-fold |
| 25d | 8.71 ± 0.08 | ∼33-fold | >100 | >384-fold |
| 27 | >100 | >116-fold | >100 | >116-fold |
| 29 | >100 | >384-fold | >100 | >384-fold |
IC50 values are reported as the mean of triplicates ± SD.
