Table 2.
Clinical Events According to the Clinical and Angiographic Risk Features
| Clinical Risk Feature |
Lesion Risk Feature |
|||||
|---|---|---|---|---|---|---|
| Low Risk | High Risk | P Value | Low Risk | High Risk | P Value | |
| MACE | 275 (6.7) | 217 (14.8) | <0.001 | 328 (7.6) | 164 (13.4) | <0.001 |
| HR: 2.512 (95% CI: 2.101-3.003); P < 0.001 | HR: 1.757 (95% CI: 1.456-2.121); P < 0.001 | |||||
| Hard endpoints | 124 (3.0) | 65 (4.4) | 0.011 | 94 (2.2) | 95 (7.8) | <0.001 |
| HR: 1.650 (95% CI: 1.221-2.230); P = 0.001 | HR: 3.710 (95% CI: 2.787-4.938); P < 0.001 | |||||
| LOCO | 133 (3.3) | 166 (11.4) | <0.001 | 209 (4.8) | 90 (7.4) | 0.001 |
| HR: 3.963 (95% CI: 3.152-4.982); P < 0.001 | HR: 1.452 (95% CI: 1.133-01.860); P = 0.003 | |||||
| All-cause death | 84 (2.1) | 133 (9.1) | <0.001 | 152 (3.5) | 65 (5.3) | 0.004 |
| Myocardial infarction | 68 (1.7) | 66 (4.5) | <0.001 | 95 (2.2) | 39 (3.2) | 0.046 |
| Target lesion revascularization | 96 (2.4) | 54 (3.7) | 0.007 | 87 (2.0) | 63 (5.2) | <0.001 |
| Target-vessel revascularization | 176 (4.3) | 77 (5.3) | 0.137 | 161 (3.7) | 92 (7.5) | <0.001 |
Values are n (%) unless otherwise indicated.
MACE = major adverse cardiac events, defined as a composite endpoint of all-cause death, myocardial infarction, target lesion revascularization; Hard endpoints = defined as all-cause death and myocardial infarction; LOCO = lesion-oriented composite outcome, defined as target lesion revascularization, target-vessel myocardial infarction.