Skip to main content
. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Curr Eye Res. 2022 Mar 25;47(6):918–922. doi: 10.1080/02713683.2022.2047205

Figure 1. Testing new and existing luciferase-tagged MYOC variants.

Figure 1.

Screening of fourteen MYOC eGLuc2 FT variants demonstrates a range of secretion characteristics. (A) Cartoon schematic of MYOC and the generated mutations. (B) Secreted Gaussia luciferase (eGLuc2) luminescence results after transfection of the indicated constructs in HEK-293A. * = p < 0.05, ** = p < 0.01, *** = p < 0.001 using a 1 sample t-test against a hypothetical value of 1 (i.e., unchanged relative to WT). n ≥ 5 independent experiments.