Table 2.
Immunologic lab data at the time of IEI diagnosis
| Parameters | HL (n = 19) | NHL (n = 36) | Leukemia (n = 9) | Solid tumor (n = 15) | p value* |
|---|---|---|---|---|---|
| Leukocyte/µl, median (IQR) | 7600 (6565–9900) | 6900 (3800–9630) | 4400 (3100–13,340) | 7100 (4290–12,600) | 0.83 |
| Lymphocyte/µl, median (IQR) | 2721 (2412–4054) | 2184 (1329–3651) | 3080 (2137–26,904) | 772 (510–2612) | 0.05* |
| Neutrophils/µl, median (IQR) | 3984 (2809–5527) | 3608 (2933–7121) | 1800 (691–73,402) | 3900 (2940–5428) | 0.85 |
| Absolute T cells/µl, median (IQR) | 2217 (1448–2856) | 1519 (763–1936) | 2022 (1167–2791) | 464 (355–665) | 0.09 |
| Absolute T4 cells/µl, median (IQR) | 552 (265–957) | 325 (134–989) | 606 (457–864) | 238 (230–340) | 0.14 |
| Absolute T8 cells/µl, median (IQR) | 2217 (1448–2856) | 1519 (763–1936) | 2022 (1167–2791) | 464 (355–665) | 0.08 |
| Absolute NK cells/µl, median (IQR) | 118 (102–129) | 231 (80–693) | 313 (125–452) | 170 (68–219) | 0.26 |
| Absolute B cells/µl, median (IQR) | 134 (46–295) | 183 (68–359) | 225 (123–540) | 38 (20–110) | 0.07 |
| Serum IgG mg/dl, median (IQR) | 587 (339–993) | 300 (71–640) | 130 (13.7–517) | 400 (46–1360) | 0.93 |
| Serum IgA mg/dl, median (IQR) | 28 (3.5–84) | 8 (2–40) | 16.5 (3.5–44) | 16 (4–37.5) | 0.92 |
| Serum IgM mg/dl, median (IQR) | 49 (15–123) | 41 (20–117) | 24 (8.5–64) | 67 (22–122) | 0.65 |
| Serum IgE IU/ml, median (IQR) | 3 (0.07–14) | 25 (0.9–226) | 1 (0.5–1.5) | 10 (4.8–11,705) | 0.35 |
*p-value calculated to indicate significant differences between hematologic and solid tumors