Table 3.

Common adverse events

Adverse Events	All Grades			Grade ≥ 3
	TC group (n = 34)	T group (n = 61)	P	TC group (n = 34)	T group (n = 61)	P
Any TEAE (≥ 1)	24(70.6)	36(59.0)	0.262	11(32.4)	8(13.1)	0.025
Leukopenia	18(52.9)	2(3.3)	P < 0.001	3(8.9)	0(0.0)	0.018
Neutropenia	16(47.1)	3(4.9)	P < 0.001	5(14.7)	0(0.0)	0.002
Anemia	16(47.1)	12(19.7)	0.005	3(8.9)	2(3.3)	P < 0.001
Thrombocytopenia	17(50.0)	5(8.2)	P < 0.001	3(8.9)	0(0.0)	0.018
Liver dysfunction	11(32.3)	9(14.8)	0.044	2(5.8)	2(3.3)	0.545
Creatinine elevation	5(14.7)	4(6.6)	0.194	0(0.0)	0(0.0)
Diarrhea	9(26.5)	13(21.3)	0.568	1(2.9)	1(1.6)	0.672
Vomiting	7(20.6)	2(3.3)	0.006	0(0.0)	0(0.0)
Stomatitis	8(23.5)	11(18.0)	0.521	0(0.0)	0(0.0)
Rash	19(55.6)	23(37.7)	0.087	4(11.7)	5(8.2)	0.569
Nail changes	7(20.6)	20(32.8)	0.268	1(2.9)	0(0.0)	0.178
Constipation	10(29.4)	6(10.0)	0.007	0(0.0)	0(0.0)

TEAE treatment-emergent adverse event