Table 1.
Characteristics of patients with severe odontogenic infections and comparison among the groups
| Patients (n = 271) | Group | P value | Trend test | ||||
|---|---|---|---|---|---|---|---|
| I (n = 123) | II (n = 61) | III (n = 74) | IV (n = 13) | P value | |||
| Age (years) | 61 [41, 74.5] | 56 [37, 71.5] | 59 [40, 77] | 65 [47.3, 73.8] | 73 [41, 75] | 0.087a | 0.011c* |
| Sex | 0.561b | 0.971d | |||||
| Male | 138 (50.9%) | 60 (48.8%) | 35 (57.4%) | 38 (51.4%) | 5 (38.5%) | ||
| Female | 133 (49.1%) | 63 (51.2%) | 26 (42.6%) | 36 (48.6%) | 8 (61.5%) | ||
| Body mass index | 22.3 [20.1, 25.0] | 22.3 [20.4, 25.1] | 23.2 [21.2, 25.2] | 21.3 [18.9, 24.8] | 21.3 [18.7, 23.4] | 0.036a* | 0.064c |
| Cause | 0.080a | 0.274d | |||||
| Apical periodontitis | 120 (44.4%) | 56 (45.9%) | 36 (59.0%) | 23 (31.1%) | 5 (38.5%) | ||
| Pericoronitis | 36 (13.3%) | 18 (14.8%) | 5 (8.2%) | 12 (16.2%) | 1 (7.7%) | ||
| Osteomyelitis | 31 (11.5%) | 12 (9.8%) | 2 (3.3%) | 14 (18.9%) | 3 (23.1%) | ||
| Post-extraction infection | 23 (8.5%) | 10 (8.2%) | 2 (3.3%) | 8 (10.8%) | 3 (23.1%) | ||
| Periodontitis | 19 (7.0%) | 5 (4.1%) | 9 (14.8%) | 4 (5.4%) | 1 (7.7%) | ||
| Others† | 42 (15.5%) | 22 (17.9%) | 7 (11.5%) | 13 (17.6%) | 0 | ||
| Lesion | 0.004a* | 0.266d | |||||
| Maxilla | 54 (20.0%) | 24 (19.7%) | 23 (37.7%) | 6 (8.1%) | 1 (7.7%) | ||
| Mandible | 212 (78.2%) | 96 (78.7%) | 37 (60.7%) | 67 (90.5%) | 12 (92.3%) | ||
| Others‡ | 5 (1.8%) | 2 (1.6%) | 1 (1.6%) | 1 (1.4%) | 0 | ||
| Location of odontogenic cause | 0.005a* | 0.403d | |||||
| Anterior | 33 (12.2%) | 12 (9.7%) | 14 (23.0%) | 6 (8.1%) | 1 (7.7%) | ||
| Premolar | 20 (7.4%) | 8 (6.5%) | 10 (16.4%) | 2 (2.7%) | 0 | ||
| Molar | 192 (70.8%) | 89 (72.4%) | 33 (54.1%) | 58 (78.4%) | 12 (92.3%) | ||
| Others§ | 26 (9.6%) | 14 (11.4%) | 4 (6.6%) | 8 (10.8%) | 0 | ||
| Compromised host¶ | 70 (25.8%) | 22 (17.9%) | 20 (32.8%) | 21 (28.4%) | 7 (53.8%) | 0.011b* | 0.006d* |
| Extent of opening mouth | 30 [15, 40] | 30 [15, 40] | 40 [25, 40] | 20 [15, 30] | 25.0 [18, 29] | < 0.001a* | 0.058c |
| Fever (°C) | 37.2 [36.7, 37.7] | 37.0 [36.6, 37.7] | 37.2 [36.7, 37.6] | 37.3 [36.6, 37.7] | 37.4 [36.9, 37.8] | 0.620a | 0.401c |
| ICU | 22 (8.1%) | 1 (0.8%) | 0 | 11 (14.9%) | 10 (76.9%) | < 0.001b* | < 0.001d* |
| Duration of intravenous antibiotics (day) | 3.5 [3.1, 4.0] | 5 [4.3, 7] | 6 [5, 8] | 8 [7, 11.3] | 12.5 [8.8, 15.3] | < 0.001a* | < 0.001c* |
| Duration of admission (day) | 9.5 [5.9, 15.2] | 7 [6, 9] | 8 [7, 11] | 14.0 [10, 18] | 25.5 [16, 36] | < 0.001a* | < 0.001c* |
Data are shown as the median [first quartile, third quartile] or n (%)
ICU intensive care unit
*Statistically significant (P < 0.05)
aKruskal − Wallis test; bFisher’s exact test; cJonckheere − Terpstra test; dCochran − Armitage test
†Odontogenic maxillary sinusitis; sialadenitis; trauma; surgical site infection; odontogenic cyst; foreign body
‡Buccal; tongue§, maxillary sinus; salivary gland; lip¶, diabetes mellitus; corticosteroids usage; hemodialysis