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Cholesterol-recognition motifs in the fusion peptide of the spike S glycoprotein from the SARS-CoV-2, SARS-CoV, and MERS-CoV, the three highly pathogenic members of the heptad human CoVs. A) FP segment (red ribbon) in the viral envelope of the SARS-CoV-2 S glycoprotein B) Close-up view of the FP in the SARS-CoV-2 S protein. C) Cholesterol-recognition motifs along the linear sequences of the FPs.
